Cortisol helps to maintain blood pressure, immune function and the body's anti- inflammatory processes. Prednisone withdrawal occurs when a person stops taking prednisone abruptly or reduces their dose too quickly. Symptoms of prednisone withdrawal can include body aches, mood swings, and extreme fatigue. Why do prednisone withdrawal symptoms happen?. J Clin Endocrinol Metab. Aug;67(2) Effect of daily and alternate day low dose prednisone on serum cortisol and adrenal androgens in hirsute.
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