Learn the causes, symptoms, treatment of bumps and bruises (contusions, Cortisone medications, such as prednisone, promote bruising by increasing the. There are many reasons why you might bruise easily. Find out if medicines you take, your age, or your health might be factors. Learn about the potential side effects of prednisone. of skin, dry scaly skin, ecchymosis and petechiae (bruising), erythema, facial edema.